Title : Exploring MAPLE deposition of bioglass and statins for implant-like surfaces
Abstract:
The controlled and precise deposition of functional coatings onto biomaterial surfaces is a pivotal aspect of modern medical and biomaterials research. Matrix Assisted Pulsed Laser Evaporation (MAPLE) has emerged as a powerful technique for achieving this, allowing the fabrication of complex and bioactive coatings. In this work, we focus on the MAPLE deposition of Bioglass and statins on implant-like surfaces. The biocompatibility and proliferation properties of our coatings was tested in vitro on 3T3 osteoblast cells. Our study's findings showed that the laser-deposited coatings are biocompatible and possess high proliferative properties. They are therefore suitable candidates for biomedical research.
Acknowledgement: This work was supported by the Romanian Ministry of Education and Research, under Romanian National Nucleu Program LAPLAS VII—contract no. 30N/2023. I.N. acknowledges the support by a grant of the Ministry of Research, Innovation and Digitization, CNCS—UEFISCDI, project no. PN-III-P2-2.1-PED-2021-3178 within PNCDI III.
Audience Take Away:
- Understanding of MAPLE Technique: Attendees will gain insights into the MAPLE technique and its significance in depositing precise and bioactive coatings onto biomaterial surfaces. They will learn about the unique advantages of MAPLE for creating complex coatings.
- Bioglass and Statin Coatings: The presentation will delve into the specific application of MAPLE in depositing Bioglass and statin coatings onto implant-like surfaces. Attendees will learn about the potential benefits of combining these materials and their implications for enhancing biocompatibility and proliferation.
- Practical Implementation: Researchers, engineers, and practitioners can apply the knowledge gained to design and develop biomaterial coatings using the MAPLE technique. They can explore the potential of combining different materials for enhanced biocompatibility and bioactivity.
- Biomedical Device Design: Professionals involved in the design of biomedical devices, such as implants, can leverage the insights to enhance the performance of their products. The use of MAPLE-deposited coatings can lead to improved integration and reduced complications.
- Teaching and Research: Faculty members can incorporate the presented research and methodology into their teaching curricula, exposing students to advanced biomaterial deposition techniques. The findings can also inspire further research in the field.
- Problem Solving: The presentation offers a practical solution for enhancing the accuracy and effectiveness of biomaterial coatings. Attendees can apply the concepts to simplify complex design challenges and contribute to the development of innovative medical solutions.
- Multidisciplinary Collaboration: The integration of MAPLE-deposited coatings opens avenues for collaboration between different fields, such as materials science, engineering, and biology. Attendees can explore interdisciplinary projects to address pressing healthcare challenges.